Hashimoto encephalopathy (HE) is an uncommon syndrome associated with Hashimoto thyroiditis Cantón A, de Fàbregas O, Tintoré M, et al. Request PDF on ResearchGate | On Jun 1, , Paloma Bacarizo and others published Encefalopatía de Hashimoto en un paciente de 20 años. CLINICAL/SCIENTIFIC NOTE. Hashimoto’s encephalopathy. Encefalite de Hashimoto. Renata Telles Rudge de AquinoI; Eduardo Genaro MutarelliII.
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Besides behavioral problems and cognitive decline, there may be fluctuating symptoms, tremor, transitory aphasia, myoclonus, ataxia, convulsions, sleep abnormalities, motor or sensory deficits and psychosis. Like other autoimmune disease improvement may occur spontaneously 4. Now, two years later, she is well and is on prednisolone 2.
ENCEFALOPATIA DE HASHIMOTO by Raul Gonçalves on Prezi
Clinically, the condition may present one or more symptoms. This improvement in the clinical presentation can be correlated to the complete resolution of the electroencephalographic changes Fig 2B. J Neurol Neurosurg Psychiatry ; Onset is often gradual and may go unnoticed by the patient and close associates to encefxlopatia patients.
Received 6 Novemberreceived in final form 30 March She was stable, suggesting a hypothalamic dysfunction. There followed a period of three years with difficulties at school. Infobox medical condition new All articles with unsourced statements Articles with unsourced statements from April Department of Medical Genetics.
It was first described in The first case of HE was described by Brain et al. Most reported cases occur during the patient’s fifth uashimoto of life. Further controlled studies of the use of steroids, plasmapheresis, or immunosuppressant medications are needed in the future to prove the concept of the pathogenic role of antithyroid antibodies in HE.
The rest of the physical examination was normal. The most common findings are diffuse or generalized slowing or frontal intermittent rhythmic delta activity.
The magnetic resonance imaging MRI of the brain showed small changes that were not significant, such as the presence of hypersignal focus in the corona radiata and bilaterally semioval center Fig 1.
In some cases, Hashimoto’s encephalopathy can show rapidly progressive dementia, myoclonus, and electroencephalographic changes with periodic recurrence of the triphasic complexes similar to those of Creutzfeldt-Jakob disease, which makes a differential diagnosis essential to both pathologies 4. Encephalomyelitis Acute disseminated Myalgic Meningoencephalitis. She was histrionic with disturbed thought. Duration of treatment is usually between 2 and 25 years.
The presence of antithyroglobulin antibody Ac-anti-Tg was not detected. Brain herniation Reye’s Hepatic encephalopathy Toxic encephalopathy Hashimoto’s encephalopathy. A possible vasculitic process has been shown in biopsy studies 7.
She had a history of hypothyroidism and did not use any medication. Focal Generalised Status epilepticus Myoclonic epilepsy. At admission, she was sleepy, disoriented, showing myoclonus, paratonia on the back of the head and arms, her deep reflexes were symmetrical with plantar flexion response and suction and hashlmoto reflexes were present.
Prion diseases encefalopatja under compulsory notification in Brazil: J Clin Endocrinol Metab ; Hashimoto’s encephalitis as a differential diagnosis of Creutzfeldt-Jakob disease.
Hashimoto’s encephalopathy mimicking Creutzfeldt-Jakob disease: Hashimoto’s disease and encephalopathy. Diagnostic criteria are encephalopathy with elevated anti-thyroid antibodies in the absence of infection, tumour or alteration in the encefalopatka vascular system.
The electroencephalogram EEG at admission was abnormal, with slow, monomorphic, occasionally sharp, triphasic, with theta-delta frequency ranges from 2 to 3 Hz, intermittent, bilateral waves, predominantly in the temporoparietal regions Fig 2A.
Encefalopattia have been no controlled trials so the optimal treatment is not known. Encephalitis Viral encephalitis Herpesviral encephalitis Limbic encephalitis Encephalitis lethargica Cavernous sinus thrombosis Brain abscess Amoebic.
However, the final diagnosis is obtained through a neuropathological exam 9. Hashimoto’s disease and encephalopathy. Alopecia is associated with polyglandular autoimmunity.
Received 18 Junereceived in final form 1 September Recent studies have shown the presence of anti-thyroid antibodies in the CSF 5 and alpha-enolase antibodies in the serum of patients with Hashimoto’s encephalopathy, suggesting the involvement of an autoimmune mechanism in this condition 6.
Since then, about cases have been described We describe the case of a patient with Hashimoto’s encephalopathy who showed clinical manifestations similar to those of Creutzfeldt-Jakob disease.